Medindia

X

Researchers Reveal Science Behind Anthrax Toxins Causing Illness and Death

by Bidita Debnath on  September 1, 2013 at 8:30 PM Research News   - G J E 4
Cells in 2 distinct areas of the body is being identified by researchers that are simultaneously targeted for damage by anthrax toxins, which results in illness and sometimes death.
 Researchers Reveal Science Behind Anthrax Toxins Causing Illness and Death
Researchers Reveal Science Behind Anthrax Toxins Causing Illness and Death
Advertisement

Findings of researchers at the National Institute of Allergy and Infectious Diseases (NIAID) and the National Heart, Lung, and Blood Institute, both part of the National Institutes of Health, are based on testing in mice.

Advertisement
According to researchers, however, the results may contribute to the development of anthrax treatments for humans.

Anthrax disease is caused by the bacterium Bacillus anthracis, which produces two deadly toxins: lethal toxin and edema toxin. When B. anthracis infects a human or animal, both toxins seek out and bind to receptors on the surfaces of human and animal cells.

Using two types of laboratory mice-those missing the anthrax toxin receptor on a single type of cell or those having the receptor present on a single type of cell-the scientists compared disease progression among the rodents.

They concluded that anthrax-induced death is caused primarily by lethal toxin targeting heart cells and muscle cells surrounding blood vessels, and edema toxin targeting liver cells.

The study has been published online in Nature.

Source: ANI
Advertisement

Post your Comments

Comments should be on the topic and should not be abusive. The editorial team reserves the right to review and moderate the comments posted on the site.
User Avatar
* Your comment can be maximum of 2500 characters
Notify me when reply is posted I agree to the terms and conditions

You May Also Like

Advertisement
View All