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Research Provides a New Approach for Auditory Localization and Speech Understanding

by Bidita Debnath on  August 10, 2014 at 11:54 PM Research News   - G J E 4
Patients with implanted artificial cochlea often complain that they cannot recognize speech well in natural environments, especially if background noise is there.
Research Provides a New Approach for Auditory Localization and Speech Understanding
Research Provides a New Approach for Auditory Localization and Speech Understanding
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Researchers think that a poor ability to localize sound in a complex auditory environment is responsible for the weak speech perception observed under these conditions. Pentobarbital anesthesia prolongs the recovery time of responses to lagging stimulus.

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The effects of pentobarbital anesthesia on the precedence effect stem from decreased dissociation of gamma-aminobutyric acid from its receptor (i.e., it is a gamma-aminobutyric acid agonist). Therefore, Yanjun Wang and co-workers from Beijing Chaoyang Hospital, Capital Medical University in China investigated how neurons in the inferior colliculus respond to the paired sounds that produce precedence-effect illusions, and whether their firing behavior can be modulated through inhibition with gamma-aminobutyric acid.

They found that after local gamma-aminobutyric acid application, responses to the lagging stimulus were suppressed. This result, published in the Neural Regeneration Research (Vol. 9, No. 4, 2014), can provide a new approach for auditory localization and speech understanding of patients with hearing aids under background noise.

Source: Eurekalert
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