Research: Nicotine Exploits COPI to Foster Addiction

by Kathy Jones on  December 31, 2013 at 7:54 PM Research News
RSS Email Print This Page Comment
Font : A-A+

Researchers have always wondered how nicotine fosters addiction in individuals.
 Research: Nicotine Exploits COPI to Foster Addiction
Research: Nicotine Exploits COPI to Foster Addiction

Unexpectedly, the researchers discovered that nicotine's ability to up-regulate* nAChRs relied on the retrograde transport of ∝6* nAChRs back from the Golgi to the ER by COPI-coated vesicles. The authors believe that Golgi-ER cycling (involving COPI vesicles) may be a common mechanism for up-regulation of other nAChRs by nicotine. Manipulation of this process could therefore help form new strategies for smoking cessation and neuroprotection against Parkinson's disease.



Source: Eurekalert

Post your Comments

Comments should be on the topic and should not be abusive. The editorial team reserves the right to review and moderate the comments posted on the site.
* Your comment can be maximum of 2500 characters
Notify me when reply is posted
I agree to the terms and conditions

More News on:

Smoking And Cancer Smoking And Tobacco Cannabis Drug Abuse Drug Detox Cigarette Smoking - A Silent Killer 

News A - Z

A B C D E F G H I J K L M N O P Q R S T U V W X Y Z

News Search

Medindia Newsletters

Subscribe to our Free Newsletters!

Terms & Conditions and Privacy Policy.

Stay Connected

  • Available on the Android Market
  • Available on the App Store

Facebook

News Category

News Archive