Research Explores Use of Salvianolate for Treatment of Cerebral Ischemia-Reperfusion Injuries

by Kathy Jones on  October 27, 2013 at 10:52 PM Research News
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Previous research has shown that salvianolic acid B is a phenolic acid compound composed of three Danshensu units and one molecule of caffeic acid.
 Research Explores Use of Salvianolate for Treatment of Cerebral Ischemia-Reperfusion Injuries
Research Explores Use of Salvianolate for Treatment of Cerebral Ischemia-Reperfusion Injuries

Salvianolic acid B exerts strong resistance to oxidative stress and inflammatory reaction, and improves energy metabolism against cerebral ischemia-reperfusion injuries. Dr. Wei Lu and his team from the Second Xiangya Hospital, Central South University, China found that administration of salvianolate during reperfusion after ischemia appears to attenuate brain tissue damage and inhibit neuronal apoptosis by increasing heat shock protein 22 and phosphorylated protein kinase B expression. These findings were published in the Neural Regeneration Research (Vol. 8, No. 25, 2013).



Source: Eurekalert

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