Recent Discovery Paves Way for New Strategies to Treat Allergic Diseases

by Sheela Philomena on  February 28, 2012 at 11:33 AM Respiratory Disease News
RSS Email Print This Page Comment bookmark
Font : A-A+

New processes that lead to the development of a novel cell implicated in allergies has been discovered by Trinity College Dublin and the United Kingdom researchers. The findings have been published in the leading international journal Nature Immunology.
 Recent Discovery Paves Way for New Strategies to Treat Allergic Diseases
Recent Discovery Paves Way for New Strategies to Treat Allergic Diseases

The work was performed by Professor Padraic Fallon, Science Foundation Ireland Stokes Professor of Translational Immunology of TCD's School of Medicine and Dr Andrew McKenzie of the Medical Research Council Laboratory for Molecular Biology in Cambridge.

The number of people with allergic disease, such as asthma and atopic dermatitis, is increasing globally with Irish children having the fourth highest incidence of asthma in the world. A major area of research in developing new strategies to treat allergic diseases is directed towards increasing understanding of the processes and cells involved that cause allergic inflammation.

Professor Fallon and colleagues previously discovered a new white blood cell, the nuocyte, that initiates the early generation of the immune responses that can lead to asthma or other allergic conditions. In this study, a new pathway for the development of nuocytes was identified and a transcription factor, RORalpha, was shown to be critical for both the generation of nucoytes and allergic-like inflammation.

This new finding identifies targets for allergic diseases that could be developed into new therapeutic strategies. Professor Fallon's research on allergies is supported by Science Foundation Ireland, The Wellcome Trust, Health Research Board and National Children's Research Centre, Ireland.

Source: Eurekalert

Post a Comment

Comments should be on the topic and should not be abusive. The editorial team reserves the right to review and moderate the comments posted on the site.
Notify me when reply is posted
I agree to the terms and conditions

More News on:

Allergy Dealing with Pollen Allergy 

News A - Z

A B C D E F G H I J K L M N O P Q R S T U V W X Y Z

News Search

Medindia Newsletters

Subscribe to our Free Newsletters!

Terms & Conditions and Privacy Policy.

Find a Doctor

Stay Connected

  • Available on the Android Market
  • Available on the App Store

Facebook

News Category

News Archive