Medindia

X

Prenatal Alcohol Exposure may Lead to Fetal Alcohol Syndrome

by Bidita Debnath on  September 15, 2013 at 11:30 PM Research News   - G J E 4
Animal experiments and clinical literature have shown that prenatal alcohol exposure in utero, especially during the early stages of pregnancy can cause fetal alcohol syndrome.
 Prenatal Alcohol Exposure may Lead to Fetal Alcohol Syndrome
Prenatal Alcohol Exposure may Lead to Fetal Alcohol Syndrome
Advertisement

The pharmacological and toxicological mechanisms of ethanol are considered to be related to the effects of ceramide. As an important signal transduction molecule, ceramide participates in a variety of cellular transduction pathways and can modulate cell cycle, cellular differentiation, proliferation, and apoptosis.

Advertisement
A recent study, published in the Neural Regeneration Research (Vol. 8, No. 23, 2013), verified that ceramide is involved in alcohol-induced neural proliferation in the hippocampal dentate gyrus of pups after prenatal ethanol exposure, and the mechanism may be associated with increased ex-pression of protein kinase C α activating the ceramide/ceramide-1-phosphate pathway.

Authors, Zhixin Wang and colleagues from Henan University, believe that this study preliminarily explains the mechanism underlying fetal alcohol syndrome caused byprenatal ethanol exposure.

Source: Eurekalert
Advertisement

Post your Comments

Comments should be on the topic and should not be abusive. The editorial team reserves the right to review and moderate the comments posted on the site.
User Avatar
* Your comment can be maximum of 2500 characters
Notify me when reply is posted I agree to the terms and conditions

You May Also Like

Advertisement
View All