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Possible Target For Treating Autoimmune Diseases Uncovered
The researchers then explored whether the womans antibodies effectively could inhibit an autoimmune response in mice.
Antibodies against the S1P receptor, created from the patients antibody-producing cells, were injected into mice that were induced to develop colitis.
The result was a significant reduction in severity of their diseases, including colitis-associated weight loss, in those mice compared to mice that did not receive the antibodies.
"These results have broad biological implications, since the cells that carry out our immune responses are present in every organ," said Goetzl, director of UCSF Allergy and Immunology Research.
The study appears in online edition of "The FASEB Journal," the official journal of the Federation of American Societies for Experimental Biology.
Source-ANI
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More News on: Chemotherapy, Chemotherapy Drugs, Myasthenia Gravis, Multiple Sclerosis Treatment and Modify, Vitiligo, Autoimmune Disorders, Wegeners Granulomatosis, Microscopic Polyangiitis, Goodpasture Syndrome
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