Medindia

X

Phenomenon Behind the Lack of Reproduction in Human Cardiac Muscle Cells Decoded

by Reshma Anand on  August 10, 2015 at 5:46 PM Research News   - G J E 4
A theory for restoring the reproduction ability of cardiac muscle cells that disappear shortly after birth has been developed by researchers.
Phenomenon Behind the Lack of Reproduction in Human Cardiac Muscle Cells Decoded
Phenomenon Behind the Lack of Reproduction in Human Cardiac Muscle Cells Decoded
Advertisement

Researcher Felix B. Engel from the University of Erlangen claims that he has discovered that the centrosome in cardiac muscle cells undergoes a process of disassembly which is completed shortly after birth.

Advertisement
He added that this disassembly process proceeds by some proteins leaving the centrosome and relocating to the membrane of the cell nucleus in which the DNA is stored and this process causes the centrosome to break down into the two centrioles of which it is composed, and this causes the cell to lose its ability to reproduce.

During the study the researchers have also investigated that whether the state of centrosome integrity is regulated naturally in the animal kingdom in order to control the reproduction of certain cells.

Researcher David Zebrowski said that they were incredibly surprised to discover that the centrosome in the cardiac muscle cells of zebrafish and amphibians remains intact into adulthood. This is the first time that they have discovered a significant difference between the cardiac muscle cells of mammals and those of zebrafish and amphibians that presents a possible explanation as to why the human heart cannot regenerate.

Further, the researchers have claimed that their research can enable new forms of medical treatment and can help researchers in developing methods of inhibiting the uncontrolled growth of cancer cells. The study is published in the journal eLife.

Source: ANI
Advertisement

Post your Comments

Comments should be on the topic and should not be abusive. The editorial team reserves the right to review and moderate the comments posted on the site.
User Avatar
* Your comment can be maximum of 2500 characters
Notify me when reply is posted I agree to the terms and conditions

You May Also Like

Advertisement
View All