People Tend to Consume Fatty Foods Excessively Due to Faulty Brain Signaling

by Reshma Anand on  September 23, 2015 at 10:46 AM Diet & Nutrition News
RSS Email Print This Page Comment
Font : A-A+

A high fat diet leads to overeating because of faulty brain signaling, reveals a new study. In the study, researchers studied one particular signaling pathway in the brain-insulin signaling and the way it works in specific brain cell circuits.
People Tend to Consume Fatty Foods Excessively Due to Faulty Brain Signaling
People Tend to Consume Fatty Foods Excessively Due to Faulty Brain Signaling

Rapamycin complex 2 (mTORC2) is a group of proteins involved in insulin signaling in the brain. The researchers wanted to find out how insulin signaling and mTORC2 affect how rewarding high fat foods are. They genetically altered brain cells in mice by taking out a part of mTORC2 and found that the mice without a functioning mTORC2 ate high-fat food excessively.

However, when provided only with low-fat food they did not overeat. They also found that the mice whose mTORC2 does not function also had less dopamine in specific regions of the brain which is associated with obesity in humans and animals, and also in escalating substance abuse.

Author Aurelio Galli said that their findings revealed a system that was designed to control eating of rewarding foods that were high in fat and possibly sugar, adding that this system could be hijacked by the very foods that it was designed to control.

He said that eating a high-fat or high-carbohydrate diet felt rewarding, but also appeared to cause changes in the brain areas that were involved in controlling eating, by causing for example insulin resistance.

Galli concluded that their study showed that when specific signaling in these areas of the brain was disrupted, it led to a vicious cycle of increasing, escalating high-fat diet intake which likely further cemented changes in these brain areas. The study is published in the Journal Heliyon.

Source: ANI

Post a Comment

Comments should be on the topic and should not be abusive. The editorial team reserves the right to review and moderate the comments posted on the site.
* Your comment can be maximum of 2500 characters
Notify me when reply is posted
I agree to the terms and conditions

Related Links

More News on:

Parkinsons Disease Parkinsons Disease Surgical Treatment Why Do We Eat - Nutrition Facts Diet Lifestyle and Heart Disease Brain Brain Facts Ataxia Low Saturated Fat and Low Cholesterol Diet Label Lingo on Food Items: Decoded Tips for Healthy Fasting During Ramadhan 

News A - Z

A B C D E F G H I J K L M N O P Q R S T U V W X Y Z

News Search

Medindia Newsletters

Subscribe to our Free Newsletters!

Terms & Conditions and Privacy Policy.

Stay Connected

  • Available on the Android Market
  • Available on the App Store

Facebook

News Category

News Archive