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Obesity Accelerates Liver Aging, Shows Research

by Vishnuprasad on  October 11, 2014 at 7:21 PM Obesity News   - G J E 4
A new research has revealed that obesity greatly accelerates aging of the liver, which might explain the early onset of many age-related diseases, including liver cancer, in obese people.
Obesity Accelerates Liver Aging, Shows Research
Obesity Accelerates Liver Aging, Shows Research
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According to the scientists at UCLA, who recently developed biomarker of aging known as an epigenetic clock, carrying excessive weight can negatively impact select human tissues.

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Study's first author Steve Horvath said that this is the first study that evaluated the effect of body weight on the biological ages of a variety of human tissues and given the obesity epidemic in the Western world, the results of this study are highly relevant for public health.

Horvath's aging clock uses a previously unknown time-keeping mechanism in the body to accurately gauge the age of diverse human organs, tissues and cell types. He and his collaborators focused on a naturally occurring process called methylation, a chemical modification of the DNA molecule and proved accurate in matching biological to chronological age in lean subjects. But liver tissues from obese subjects tended to have a higher biological age than expected.

The study was published in the journal Proceedings of the National Academy of Sciences.

Source: ANI
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