Novel 3-D Heart to Help Improve Cardiac Treatment

by Shirley Johanna on  February 11, 2017 at 1:04 PM Heart Disease News
RSS Email Print This Page Comment bookmark
Font : A-A+

A new method has been developed to create three dimensional (3-D) heart tissue that beats in synchronized harmony which could lead to better understanding of cardiac health and improved treatments.
Novel 3-D Heart to Help Improve Cardiac Treatment
Novel 3-D Heart to Help Improve Cardiac Treatment

"This breakthrough will allow better and earlier drug testing, and potentially eliminate harmful or toxic medications sooner," said one of the researchers Muhammad Yousaf, Professor at York University in Toronto, Canada.

Until now, most 2-D and 3-D in-vitro tissue did not beat in harmony and required scaffolding for the cells to hold onto and grow, causing limitations.

In this research, published in the journal Scientific Reports, Yousaf and his team made a scaffold free beating tissue out of three cell types found in the heart -- contractile cardiac muscle cells, connective tissue cells and vascular cells.

The researchers believe this is the first 3-D in vitro cardiac tissue with three cell types that can beat together as one entity rather than at different intervals.

In addition, the substance used to stick cells together (ViaGlue) could provide researchers with tools to create and test 3D in vitro cardiac tissue in their own laboratories to study heart disease and issues with transplantation.

Cardiovascular associated diseases are the leading cause of death globally.

"Making in vitro 3-D cardiac tissue has long presented a challenge to scientists because of the high density of cells and muscularity of the heart," Dmitry Rogozhnikov, a chemistry PhD student at York University.

"For 2-D or 3-D cardiac tissue to be functional it needs the same high cellular density and the cells must be in contact to facilitate synchronized beating," Rogozhnikov explained.

Although the 3-D cardiac tissue was created at a millimeter scale, larger versions could be made, said Yousaf, who has created a start-up company OrganoLinX to commercialize the ViaGlue reagent and to provide custom 3D tissues on demand.



Source: IANS

Post a Comment

Comments should be on the topic and should not be abusive. The editorial team reserves the right to review and moderate the comments posted on the site.
Notify me when reply is posted
I agree to the terms and conditions

Wow, that is great news for all Cardiac patients. It is a good research on medical science. 6 months before when my uncle faced Heart problem our family member scared and we have no Ideas what to do. Then my friend suggested me to contact with “Global Medical Tourism Inc” who is very famous for his medical treatment services. I contacted with then no my uncle health is improving.

Related Links

More News on:

Palpitations And Arrhythmias Heart Healthy Heart Statins Mitral Valve Prolapse Aortic Valve Stenosis Cardiomyopathy Pericarditis 

News A - Z

A B C D E F G H I J K L M N O P Q R S T U V W X Y Z

News Search

Medindia Newsletters

Subscribe to our Free Newsletters!

Terms & Conditions and Privacy Policy.

Find a Doctor

Stay Connected

  • Available on the Android Market
  • Available on the App Store

News Category

News Archive

Loading...