A new vaccine has been developed by a Michigan University researcher to combat one of the deadliest strains of E. coli bacteria that kills over two to three million children every year.
Enterotoxigenic E. Coli, (ETEC) is responsible for 60 percent to 70 percent of all E. coli diarrheal disease.
What is diarrhea?
Diarrhea is an important cause of malnutrition, main cause of death in acute diarrhea is due to dehydration, which results from the loss of fluid and electrolytes in stools.
Diarrhea is an important cause of malnutrition, main cause of death in acute diarrhea is due to dehydration, which results from the loss of fluid and electrolytes in stools.
Since the toxin was so small, it did not prompt the body's defence system to develop immunity, allowing the same individual to repeatedly get sick, often with more severe health implications.
"This strain of E. coli is an international health challenge that has a huge impact on humanity," said Saeed.
About Water Borne Diseases
Waterborne diseases are communicable diseases caused by diseases causing microorganisms in contaminated water. It is more prevalent during floods and in tsunami affected areas.
Waterborne diseases are communicable diseases caused by diseases causing microorganisms in contaminated water. It is more prevalent during floods and in tsunami affected areas.
Saeed created a biological carrier to attach to the toxin that once introduced into the body induces a strong immune response.
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During the study, the researchers tested the vaccine on mice and found the biological activity of the toxin was enhanced by more than 40 percent, leading to its recognition by the body's immune system.
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Saeed hopes that human clinical trials could begin late in the year.
Source-ANI
THK
