Scientists at the Northwestern University are first to invent a bioactive nanomaterial that promotes new cartilage to grow in vivo without using costly growth factors.
The therapy is minimally invasive and activates the stem cells in the bone marrow producing natural cartilage. There is no conventional therapy that can do this so far.
Achondroplasia - Causes, Symptoms, Diagnosis, Treatment
Achondroplasia is a rare genetic disorder of bone growth that causes short-limbed dwarfism. It occurs due to mutations in a single gene called the FGFR3.
Achondroplasia is a rare genetic disorder of bone growth that causes short-limbed dwarfism. It occurs due to mutations in a single gene called the FGFR3.
Assistant Professor Ramille Shah, first author of the study, said: "Our material of nanoscopic fibers stimulates stem cells present in bone marrow to produce cartilage containing type II collagen and repair the damaged joint."
"A procedure called microfracture is the most common technique currently used by doctors, but it tends to produce a cartilage having predominantly type I collagen which is more like scar tissue," Shah added.
Quality of Life of Osteoarthritis Patients can be Improved by Cartilage Repair
Repairing cartilaginous tissue may help improve quality of life of patients suffering from osteoarthritis, a new study has said.
Repairing cartilaginous tissue may help improve quality of life of patients suffering from osteoarthritis, a new study has said.
Source-ANI
TRI
Tissue Engineered Scaffolding Allows Reproduction of Cartilage Tissue
A new study examines the use of tissue-engineered scaffolding made of cartilage cells, which have a limited ability to heal naturally
A new study examines the use of tissue-engineered scaffolding made of cartilage cells, which have a limited ability to heal naturally
Diseased Cartilage Harbors Unique Migratory Progenitor Cells
A new study finds previously unidentified fibrocartilage-forming progenitor cells in degenerating, diseased human cartilage, but not in cartilage from healthy joints.
A new study finds previously unidentified fibrocartilage-forming progenitor cells in degenerating, diseased human cartilage, but not in cartilage from healthy joints.
