Medindia

X

New Hormone may Help Restore Fertility in Women

by Dr. Enozia Vakil on  May 31, 2013 at 6:59 PM Women Health News   - G J E 4
New treatments to restore fertility in women is on the way, thanks to a newly discovered hormone, produced by the human eggs.
 New Hormone may Help Restore Fertility in Women
New Hormone may Help Restore Fertility in Women
Advertisement

"The finding of a new ovarian hormone produced by the oocytes capable of stimulating ovarian follicle growth could lead to new infertility treatments," said Aaron J. W. Hsueh, Ph.D., a researcher involved in the work from the Division of Reproductive and Stem Cell Biology in the Department of Obstetrics and Genecology at Stanford University Medical School in Stanford, California.

Advertisement
To make this discovery, Hsueh and colleagues analyzed all the proteins likely made by the eggs, and discovered a previously unknown hormone, called R-spondin2. The researchers then replicated this new hormone in test tubes and injected it into mice. The hormone stimulated growth of mouse ovarian cells, leading to the generation of mature eggs. These eggs were fertilized and led to successful pregnancies and the delivery of healthy pups. Then, human ovarian tissue was grafted into mice, and this also grew after treatment with this newly identified ovarian hormone, suggesting that the hormone could work in humans. The researchers speculate that when used in conjunction with the traditional Follicle Stimulating Hormone (FSH), this newly discovered ovarian hormone could lead to new infertility treatment options for those not responding well to FSH treatment alone.

"Infertility can be very frustrating for couples who have been trying to conceive for a very long time. The discovery of this new hormone is a potential game-changer in human fertility treatment," said Gerald Weissmann, M.D., Editor-in-Chief of The FASEB Journal, "but further research is needed to determine its efficacy and safety in humans."



Source: Eurekalert
Advertisement

Post your Comments

Comments should be on the topic and should not be abusive. The editorial team reserves the right to review and moderate the comments posted on the site.
User Avatar
* Your comment can be maximum of 2500 characters
Notify me when reply is posted I agree to the terms and conditions

You May Also Like

Advertisement
View All