New Genes Linked to Multiple Sclerosis Uncovered

Three genes and their expressed proteins that are associated with the pathogenesis of multiple sclerosis have been discovered.

By comparing information on the genes and proteins expressed in the brains of thousands of individuals with and without multiple sclerosis, investigators discovered different expression levels of the SHMT1, FAM120B, and ICA1L genes (and their proteins) in brain tissues of patients versus controls.

What is Multiple Sclerosis

Multiple Sclerosis, or MS, affects more than a million people worldwide. In India there are 40,000 - 50,000 people estimated to be affected by the disease. It frequently attacks young people, usually in the age group of 20-40 years, and is more common among females than males.

Multiple sclerosis - Symptoms - Causes - Diagnosis - Treatment
Multiple sclerosis can be a severely disabling autoimmune disease that affects the myelin or insulating layer of the nerve fibers and typically has remissions and relapses

‘Studying the functions of the newly identified genes may uncover new information on the mechanisms involved in the development and progression of multiple sclerosis.’

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“Our findings shed new light on the pathogenesis of MS and prioritized promising targets for future therapy research,” the authors wrote.

Source-Eurekalert

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