New Engineered 'Glucose-Responsive Insulin' may Control Diabetes More Efficiently

by Dr. Trupti Shirole on  February 16, 2015 at 9:43 AM Diabetes News
RSS Email Print This Page Comment bookmark
Font : A-A+

A new engineered insulin for diabetes patients hopes to improve the treatment as insulin is critical to maintain good health and normal blood-sugar levels (BSL), revealed a study conducted at Koch Institute.
 New Engineered 'Glucose-Responsive Insulin' may Control Diabetes More Efficiently
New Engineered 'Glucose-Responsive Insulin' may Control Diabetes More Efficiently

Researchers showed that their modified insulin can circulate in the bloodstream for at least 10 hours, and that it responds rapidly to changes in blood-sugar levels. This could eliminate the need for diabetic patients to repeatedly monitor their BSL and inject insulin throughout the day.

Researcher Daniel Anderson, said, "The real challenge was to get the right amount of insulin available when one needs it, because if one has too little insulin their blood sugar goes up, and if one have too much, it can go dangerously low, a condition known as hypoglycemia that can lead to shock and even death."

To create this glucose-responsive insulin, the research team first added a hydrophobic molecule called an aliphatic domain, which is a long chain of fatty molecules dangling from the insulin molecule. This helps the insulin circulate in the bloodstream for a longer duration. Researchers do not yet know exactly the reason for this phenomenon. They suggest that the fatty tail may bind to albumin, a protein found in the bloodstream, sequestering the insulin and preventing it from latching onto sugar molecules.

Anderson said, "Giving this type of insulin once a day instead of long-acting insulin could offer patients a better alternative that reduces their blood-sugar swings, which can cause health problems when they continue for years and decades."

Source: Medindia

Post a Comment

Comments should be on the topic and should not be abusive. The editorial team reserves the right to review and moderate the comments posted on the site.
Notify me when reply is posted
I agree to the terms and conditions

Related Links

More News on:

Diabetic Retinopathy Diabetes Diabetic Diet Diabetes - Essentials Diabetes - Self-Monitoring of Blood Glucose (SMBG) Insulin Delivery Devices Diabetes and Exercise Stress Relief Through Alternative Medicine Stress and the Gender Divide Silent Killer Diseases 

News A - Z

A B C D E F G H I J K L M N O P Q R S T U V W X Y Z

News Search

Medindia Newsletters

Subscribe to our Free Newsletters!

Terms & Conditions and Privacy Policy.

Find a Doctor
Advertisement

Stay Connected

  • Available on the Android Market
  • Available on the App Store

Facebook

News Category

News Archive