New Discovery Offers Hope Against Recurrent Breast Cancer

by Sheela Philomena on  February 11, 2013 at 4:16 PM Cancer News
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A protein that is highly expressed in triple negative breast cancer cells has been discovered by researchers. Due to chemotherapy resistance and a high rate of relapse, triple negative cancers are among the most difficult breast cancers to treat.
 New Discovery Offers Hope Against Recurrent Breast Cancer
New Discovery Offers Hope Against Recurrent Breast Cancer

Researchers led by Carlos Arteaga at Vanderbilt University made a mouse model of breast cancer, in which the protein both diverted cells down a path to becoming cancerous and allowed for cancer to come back after treatment.

Importantly, loss of the protein prevented tumor recurrence in mice.

These studies identify a mechanism by which cancer cells elude standard chemotherapy and provide a rationale for testing the therapeutic potential of agents that block the protein.

The study has been published in the Journal of Clinical Investigation.

Source: ANI

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