Two recent studies have suggested that medicines to prevent or treat migraines in adults are not effective in relieving headaches in children, which may be an indication that doctors need to re-look at the use of drugs in pediatric patients.
Johnson and Johnson's seizure medicine Topamax and the antidepressant trazodone have no proven benefits to show that it can be used in children, an analysis of past studies has shown.
AdvertisementAccording to statistics, nearly 8 million kids in the U.S., get migraines. The results point out the need for more studies to evaluate the use of adult migraine medicines in kids.
"Pediatric clinical trials are different than trials conducted in adults for many reasons. One of the issues is that a failed pediatric trial seldom motivates a sponsor to conduct additional pediatric trials. This is in contrast to what happens with failed adult trials. It has to do with the fact the sponsor is usually much more interested in the adult market as the pediatric populations with diseases are small."
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