Migraine Paves Way for Dopamine-Based Therapies

by Bidita Debnath on  March 30, 2017 at 11:41 PM Research News
RSS Email Print This Page Comment bookmark
Font : A-A+

Dopamine levels fall during the migraine attacks, shows a recent research. Using PET scans of the brain, the University of Michigan researchers showed that dopamine falls and fluctuates at different times during a migraine headache.
 Migraine Paves Way for Dopamine-Based Therapies
Migraine Paves Way for Dopamine-Based Therapies

This could help scientists better understand dopamine-based therapies for migraines as well as a patient's behaviour during an attack. The connection between dopamine and migraines has long been a poorly understood therapeutic and research area, said researcher Alex DaSilva. Dopamine, sometimes called the brain's feel-good neurotransmitter, helps regulate emotion, motivation and sensory perception.

Physicians and emergency rooms often give migraine patients dopamine antagonists, drugs that block overactive dopamine receptors, to level off wild dopamine fluctuations and ease migraine attacks. DaSilva and colleagues took various measurements of brain activity and dopamine levels of eight migraine sufferers and eight healthy patients during migraine attacks and between headaches.

They compared study participants to each other with and without headaches, and also migraineurs to healthy patients. When migraine patients were between headaches, their dopamine levels were as stable and even as the healthy patients, DaSilva said. But during an attack, the migraine patients' dopamine levels fell significantly.

"This dopamine reduction and fluctuation during the migraine attack is your brain telling you that something is not going well internally, and that you need time to heal by forcing you to slow down, go to a dark room and avoid any kind of stimulation," he said. The study appears in the journal Neurology.

Source: ANI

Post a Comment

Comments should be on the topic and should not be abusive. The editorial team reserves the right to review and moderate the comments posted on the site.
Notify me when reply is posted
I agree to the terms and conditions

Related Links

More News on:

Migraine Headache / Cephalgia Headache Symptom Evaluation Retinal Migraine / Ocular Migraine Menstrual Migraine 

News A - Z

A B C D E F G H I J K L M N O P Q R S T U V W X Y Z

News Search

Medindia Newsletters

Subscribe to our Free Newsletters!

Terms & Conditions and Privacy Policy.

Find a Doctor

Stay Connected

  • Available on the Android Market
  • Available on the App Store

News Category

News Archive

Loading...