Mass Spectrometry Detects 10 Protein Spots After Acute High-Altitude HBI

by Bidita Debnath on  January 2, 2014 at 11:35 PM Research News
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Hypobaric hypoxia is involved in hypoxic brain injury and can cause severe brain damage and mitochondrial dysfunction.
 Mass Spectrometry Detects 10 Protein Spots After Acute High-Altitude HBI
Mass Spectrometry Detects 10 Protein Spots After Acute High-Altitude HBI

Dr. Jianyu Li and colleagues from Logistics College of Chinese People's Armed Police Forces evaluated the degree of brain damage with different exposure times to hypoxia and further investigate the differential expression of cerebral mitochondrial proteins by comparative proteomic analysis, in a broader attempt to search for treatment targets of hypobaric hypoxia brain injury. Furthermore, ten protein spots were selected and identified by mass spectrometry.

These ten proteins are all involved in the electron transport chain and the function of ATP synthase. These findings were published in the Neural Regeneration Research (Vol. 8, No. 31, 2013).

Source: Eurekalert

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