Researchers at Vanderbilt University are currently investigating how iron deficiency influences gastric cancer caused due to H.pylori, a bacteria that causes gastric ulcers, according to a new study published in the Journal of Clinical Investigation.
Peek and colleagues found that low iron accelerated the development of H. pylori-associated cancerous lesions in gerbils. Further, H. pylori strains isolated from a human population at high risk for gastric cancer were more virulent and produced greater inflammation if they came from patients with low iron levels. In an accompanying article, El-Omar Emad of Aberdeen University discusses how iron levels could be used to identify patients that are at a higher risk for gastric cancer after H. pylori infection.
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