Industrialization, World War I, Soviet Collapse Helped Spread of Drug-resistant Tuberculosis

by Dr. Trupti Shirole on  January 20, 2015 at 10:53 AM Research News
RSS Email Print This Page Comment
Font : A-A+

Some of the drug-resistant tuberculosis (TB) bacteria have spread from East Asia in waves propelled by industrialization, World War I and Soviet collapse, according to a study published in the journal Nature Genetics. Researchers studied nearly 5,000 TB samples from 99 countries and pinpointed changes in the DNA code to draw a partial family tree of the germ Mycobacterium tuberculosis.
 Industrialization, World War I, Soviet Collapse Helped Spread of Drug-resistant Tuberculosis
Industrialization, World War I, Soviet Collapse Helped Spread of Drug-resistant Tuberculosis

Researchers claim that a branch of that tree known as the 'Beijing lineage' begins in a region around northeast China, Korea and Japan some 6,600 years ago. Thereafter, it evolved into several sub-lineages and strains, spreading eastward to Micronesia and Polynesia and westward to central Asia, Russia and eastern Europe. The migration waves have become more pronounced over the past two centuries, owing to industrialization and urbanization, as well as episodes of widespread deprivation like World War I that brought infected and vulnerable people close together.

Study co-author Thierry Wirth said, "Among the toughest modern-day versions, two multidrug resistant (MDR) clones, started spreading through eastern Europe and Asia on an epidemic scale about 20-30 years ago, coinciding with the collapse of the public health system of the former Soviet Union."

Only a single decrease was visible on a chart plotting the global spread of the 'Beijing lineage' from the year 1500 to 2000, which coincided with a rise in antibiotic use in the 1960s and ended with the HIV epidemic from the 1980s.

TB is theorized to be about 40,000 years old. MDR strains, which do not respond to front-line antibiotics, are a major concern as they are costly and difficult to treat. Unraveling the disease's genetic history may offer pointers for tackling its spread.

Source: Medindia

Post a Comment

Comments should be on the topic and should not be abusive. The editorial team reserves the right to review and moderate the comments posted on the site.
Notify me when reply is posted
I agree to the terms and conditions

Related Links

More News on:

Tuberculosis Tracheostomy Pleural Effusion Silicosis Screening Tests for Tuberculosis Fever Cough Symptom Evaluation Warts Diet in Tuberculosis Stomach Tuberculosis 

News A - Z

A B C D E F G H I J K L M N O P Q R S T U V W X Y Z

News Search

Medindia Newsletters

Subscribe to our Free Newsletters!

Terms & Conditions and Privacy Policy.

Advertisement
Advertisement

Stay Connected

  • Available on the Android Market
  • Available on the App Store

Facebook

News Category

News Archive