A new research has revealed that blood sugar level in type 2 diabetics can be better controlled with a high energy breakfast and low energy dinner, as compared to a low energy breakfast and high energy dinner.
The study included 18 individuals (8 men, 10 women), with type 2 diabetes of less than 10 years duration, an age range 30-70 years, body mass index (BMI) 22-35 kg/m2, and treated with metformin and/or dietary advice (eight patients with diet alone and 10 with diet and metformin).
The results showed that post-meal glucose levels were 20 percent lower and levels of insulin, C-peptide and GLP-1 were 20 percent higher in participants on the B diet compared with the D diet. Despite the diets containing the same total energy and same calories during lunch, lunch in the B diet resulted in lower blood glucose (by 21-25 percent) and higher insulin (by 23 percent) compared with the lunch in the D diet.
Prof. Oren Froy, one of the authors of the study from Hebrew University of Jerusalem, said that the observations suggest that a change in meal timing influences the overall daily rhythm of post-meal insulin and incretin and results in a substantial reduction in the daily post-meal glucose levels. It may be a crucial factor in the improvement of glucose balance and prevention of complications in type 2 diabetes and lend further support to the role of the circadian system in metabolic regulation.
Prof. Daniela Jakubowicz concluded that high energy intake at breakfast is associated with significant reduction in overall post-meal glucose levels in diabetic patients over the entire day. The dietary adjustment may have a therapeutic advantage for the achievement of optimal metabolic control and may have the potential for being preventive for cardiovascular and other complications of type 2 diabetes.
The study is published in Diabetologia.