How Tick-Borne Bacteria Get Past a Tick's Defenses to Colonize It

by Dr. Trupti Shirole on  January 17, 2017 at 11:51 AM Research News
RSS Email Print This Page Comment bookmark
Font : A-A+

The human granulocytic anaplasmosis is the second-most-common tick-borne infection in the United States. It can cause headaches, muscle pain, and even death.
 How Tick-Borne Bacteria Get Past a Tick's Defenses to Colonize It
How Tick-Borne Bacteria Get Past a Tick's Defenses to Colonize It

Before infecting humans, tick-borne bacteria or viruses first have to get past a tick's defenses to colonize it. How this occurs is not well understood.

To investigate, Yale researchers studied a model of the human granulocytic anaplasmosis.

The researchers found that in ticks, the bacterium that causes the infection, A. phagocytophilum, triggers the expression of a particular protein. This protein alters molecules in the tick's gut, allowing the bacteria to enter and colonize the gut microbes.

"It's like a stealth warrior that indirectly changes the tick by using the tick's own defense system," said Erol Fikrig, chief of the Infectious Diseases Section at Yale School of Medicine and senior author of the study.

The unexpected finding could help scientists develop strategies to block A. phagocytophilum and other tick-borne agents that cause disease, say the researchers. Fikrig's team will explore the phenomenon in the bacterium that causes Lyme disease, and its work could have implications for other mosquito-borne infections, such as Zika and West Nile.

The study was published by the Proceedings of the National Academy of Sciences.

Source: Eurekalert

Post a Comment

Comments should be on the topic and should not be abusive. The editorial team reserves the right to review and moderate the comments posted on the site.
Notify me when reply is posted
I agree to the terms and conditions

Related Links

More News on:

Shigellosis Lyme Disease Amyotrophic Lateral Sclerosis (ALS) MRSA - The Super Bug Food Safety for Health Antibiotics Rocky Mountain Spotted Fever Relapsing Fever 

News A - Z

A B C D E F G H I J K L M N O P Q R S T U V W X Y Z

News Search

Medindia Newsletters

Subscribe to our Free Newsletters!

Terms & Conditions and Privacy Policy.

Find a Doctor

Stay Connected

  • Available on the Android Market
  • Available on the App Store

News Category

News Archive

Loading...