Houshiheisan Maintains Stabilization of Neurovascular Units

by Bidita Debnath on  July 8, 2014 at 9:25 PM Research News
RSS Email Print This Page Comment bookmark
Font : A-A+

Cerebral ischemia injure neurons, and also involves the glial cells that provide a supportive scaffold to which the neurons are attached and the microvessels that provide energy for nervous tissue.
 Houshiheisan Maintains Stabilization of Neurovascular Units
Houshiheisan Maintains Stabilization of Neurovascular Units

Therefore, protection of a single neuron is not sufficient to recover nervous function, and more attention should be paid to maintenance of the function of entire neurovascular units.

Houshiheisan compound is one of effective traditional Chinese compound prescriptions for stroke. The prescription is composed of wind-dispelling (chrysanthemun flower, divaricate saposhnikovia root, Manchurian wild ginger, cassia twig, Szechwan lovage rhizome, and platycodon root) and deficiency-nourishing (ginseng, Chinese angelica, large-head atractylodes rhizome, Indian bread, and zingiber) drugs.

Haizheng Wang and his team, School of Traditional Chinese Medicine, Capital Medical University in China, performed a study on Houshiheisan and found that the wind-dispelling and deficiency-nourishing drugs in the compound prescription Houshiheisan are complementary to each other, effectively suppress abnormal amyloid precursor protein accumulation, reduce amyloid substance deposition, maintain stabilization of the internal environment of neurovascular units, and minimize injury to neurovascular units in the ischemic penumbra by downregulating the amyloid-βexpression. Their findings were published in Neural Regeneration Research (Vol. 9, No. 7, 2014).

Hematoxylin-eosin staining revealed that after intragastric administration of Houshiheisan, the number of nerve cells was visibly increased and there was infiltration of a small number of inflammatory cells in the ischemic penumbra of rats with cerebral ischemia.

Source: Eurekalert

Post a Comment

Comments should be on the topic and should not be abusive. The editorial team reserves the right to review and moderate the comments posted on the site.
Notify me when reply is posted
I agree to the terms and conditions

News A - Z

A B C D E F G H I J K L M N O P Q R S T U V W X Y Z

News Search

Medindia Newsletters

Subscribe to our Free Newsletters!

Terms & Conditions and Privacy Policy.

Find a Doctor

Stay Connected

  • Available on the Android Market
  • Available on the App Store

Facebook

News Category

News Archive