HIV can Spread to Brain in Four Months Increasing Risk of Dementia

by Dr. Trupti Shirole on  March 28, 2015 at 6:03 AM AIDS/HIV News
RSS Email Print This Page Comment
The human immunodeficiency virus (HIV) that causes AIDS can spread to the patients' brain early in the illness process, revealed a study published in PLoS Pathogens. In the absence of antiretroviral therapy, HIV can genetically evolve and independently replicate in patients' brains as early as four months after initial infection and predisposes an individual to HIV-associated dementia. These findings stress the importance of routine HIV testing to catch the infection as early as possible to allow the prompt initiation of antiretroviral therapy.
 HIV can Spread to Brain in Four Months Increasing Risk of Dementia
HIV can Spread to Brain in Four Months Increasing Risk of Dementia
Advertisement

Ronald Swanstrom, director, Center for AIDS Research (CFAR), University of North Carolina in the US, informed that one-third of people not taking antiretroviral therapy (ART) to control their HIV will eventually develop HIV-associated dementia.

Advertisement
Researchers followed 72 participants during the first two years of HIV infection. These participants were not taking ART to control their HIV at the time of the study. Through analysis of their cerebral spinal fluid (CSF) and blood samples, 20% of the participants showed replication in the central nervous system (CNS) at four months. Additionally, 30% of participants showed evidence of a marked CSF inflammatory response in at least one time point and 16% of study volunteers showed a marked CSF inflammatory response at multiple time points, suggesting an ongoing infection in the CNS.

Swanstrom said, "This shows that viral replication and inflammation can occur early in infection with the concern being that the damage caused could be irreversible. HIV and inflammation have the potential to accelerate the aging process and cause neurocognitive impairment, in the extreme case resulting in HIV-associated dementia."

Source: Medindia
Advertisement

Post your Comments

Comments should be on the topic and should not be abusive. The editorial team reserves the right to review and moderate the comments posted on the site.
* Your comment can be maximum of 2500 characters
Notify me when reply is posted
I agree to the terms and conditions

More News on:

Oral Health And AIDS Alzheimers Disease Parkinsons Disease AIDS/HIV AIDS/HIV - Epidemiology AIDS/HIV - Clinical Features AIDS/HIV - Health Education AIDS/HIV - Prevention And Transmission AIDS / HIV - Treatment AIDS/HIV- Lab Tests and Faqs 
Advertisement

News A - Z

A B C D E F G H I J K L M N O P Q R S T U V W X Y Z

News Search

Medindia Newsletters

Subscribe to our Free Newsletters!

Terms & Conditions and Privacy Policy.

Advertisement

Advertisement
Advertisement

Stay Connected

  • Available on the Android Market
  • Available on the App Store

Facebook

News Category

News Archive