Highlights:
A new research study from the East Carolina University found that regular exercises by father’s before child conception may increase the risk of metabolic disorders like obesity and increased insulin sensitivity in their offspring’s gene.//
Preconception exercises like walking, cycling, swimming can increase the chances of pregnancy.- Preconception exercises are usually done to increase the chances of conceiving.
- Dad’s preconception exercises are found to increase the risk of obesity and insulin resistance in the offspring gene.
- The study is found to help in the future treatment of metabolic disorders.
Introduction to Metabolic Defects
Metabolism is the sum total of all chemical and physical changes that take place in any organism that enables it to function and grow.
Metabolism is the sum total of all chemical and physical changes that take place in any organism that enables it to function and grow.
‘Increased risk of metabolic disorders in the offspring are associated with dad’s preconception exercises.’
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The research was carried out by studying the offsprings of male rodents that were trained for 12 weeks.Alexander Murashov lead author and associate professor of physiology at East Carolina University said that fathers’ exercise regimen programmed the offspring to be able to burn calories more efficiently, “like [an] energy efficient car which uses less gas to run the same distance.”
The study findings found that paternal sperms were capable of changing the miRNA and metabolic genes in the offsprings.
The research team also found that the effect “may be an adaptive mechanism of changing offspring phenotypic features in response to environmental challenges experienced by fathers.”
Murashov said that the results were “a total surprise, because our initial hypothesis was that paternal long-term exercise would decrease risk for obesity in the offspring.”
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Screening (for Genetic and Other Disorders) of Embryos and Newborns: Why it is important?
Pre-Implantation Genetic Diagnosis (PGD) of embryos and New Born Screening of infants checks metabolic and inherited disorders and ensure proper growth of new born babies.
Pre-Implantation Genetic Diagnosis (PGD) of embryos and New Born Screening of infants checks metabolic and inherited disorders and ensure proper growth of new born babies.
The outcome of the study will also help in the future treatment of metabolic disorders in humans.
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Through gene therapy, the corrected liver cells were transplanted into the diseased liver of pigs with HT1, resulting in enzyme production.
