The chances of breast
cancer recurring are higher in obese women as compared to thinner females,
according to a study.
Researchers have revealed that overweight
women have bad outcomes from breast cancer.
caused by the surplus body fat and hormonal changes possibly promote the
recurrence of breast cancer.
Earlier, it was
presumed that inadequate treatment with chemotherapy drugs was responsible for
increased risk of recurrence in overweight individuals. Treatment was thought
to be inadequate since obese women received drug doses aimed at slimmer
Dr. Joseph Sparano, of
the Albert Einstein College of Medicine's Montefiore Medical Center in New
York, who conducted a recent research involving around 7,000 women patients,
said, "'We found that obesity at diagnosis is associated with about a 30 per
cent higher risk of recurrence and a nearly 50 per cent higher risk of death,
despite optimal treatment." The study was published in CANCER, a journal of the
American Cancer Society.
The volunteers had normal kidney, heart, bone
marrow and liver function. This helped the scientists to disentangle the
association of obesity from other factors.
It was noticed that a
higher body mass index (BMI) considerably increased the risk of breast cancer
recurrence and premature death despite hormonal therapy and chemotherapy.
Dr. Sparano mentioned
that increasing weight leads to greater risk of recurrence via higher insulin
It was uncertain if
losing weight after diagnosis could cut the risk of recurrence, but some
studies suggest this approach reduces insulin levels, which might be effective.
who is a clinical nurse specialist at Breast Cancer Care stated, 'We know a
healthy weight is beneficial for reducing the risk of a range of health
"So, while this
study may be useful, it's important to put this into perspective. There are a
number of key features of breast cancer that will influence the risk of it
coming back and each person's predicted outlook will vary.
"For those who
have been diagnosed, there is emerging evidence that maintaining a healthy
weight, as well as being physically active may help reduce the risk of the
can be really difficult as weight gain can be a common side-effect of
Dr, Stuart Griffiths,
the head of commissioned research, Breast Cancer Campaign was of the opinion
that the findings of the study provided sufficient evidences of obesity having
a harmful and detrimental effect on the breast cancer recurrence. After
menopause, the risk of breast cancer can be diminished by maintaining healthy
extremely important to control increasing weight as obesity can increase the
chances of breast cancer.