new research report published recently has evaluated the role of Magnetic Resonance Enterography (MRE)
amongst children having spondyloarthritis.
is a group of many types of inflammatory arthritic conditions including
arthritis associated with inflammatory bowel disease (IBD). Spondyloarthritis
generally attacks the spine and in some cases, the joints of arms and legs.
Resonance Enterography is commonly used to diagnose and monitor Inflammatory Bowel Disease (IBD). It is
the preferred choice over Computed Tomography for evaluation of IBD as it is a
non-invasive, radiation free interrogation. Although colonoscopy is usually
used in the final diagnosis and detecting changes in IBD, the cost involved is
is one of the first studies to evaluate
the role of MRE in studying the changes in gut inflammation amongst children
this small pilot study, five children, four with spondyloarthritis and one with
juvenile idiopathic arthritis were identified for sub-clinical inflammatory
bowel disease diagnosed using the fecal test.
children were identified with signs of IBD. The findings included -
thickening and uptake of contrast agent at the distal end of the small
intestine in one child;
uptake of the contrast medium in the distal end of the small intestine and no
thickening in the second child; and
prominent vasa recta (intestinal arteries) and mesenteric lymph nodes (lymph
nodes that lie between the lining of the abdominal cavity connecting the
duodenum and small intestine to the back wall of the abdomen) in the third
was conducted in the case showing changes in the distal end of the small
intestine which confirmed inflammatory bowel disease.
researchers found that the use of MRE
amongst children with sub-clinical inflammatory bowel disease was
well-tolerated and practical. It shows the possibility of the use of this
test to screen sub-clinical bowel disease.
Reference: MR enterography to evaluate sub-clinical
intestinal inflammation in children with spondyloarthritis; Mathew Stoll et al;
BMC Pediatric Rheumatology 2012.