Low levels of male sex hormones are associated with increased urine output at night, finds a new study from South Korea. This association has been found to be independent of both age and prostate volume.
Low levels of testosterone, the male sex hormone, were found to be linked with 93% greater odds for nocturia. Nocturia is a condition in which an individual has to wake up at night one or more times for passing urine. Nocturia has a wide range of causes ranging from increased fluid intake to malignancies. It becomes more common as people age and occurs in both men and women.
AdvertisementThe study included 2180 patients who attended an outpatient urologic clinic between July 2011 and August 2012 for lower urinary tract symptom complaints.
The study found that every 0.142 ng/mL decrease in testosterone was associated with an increase in the number of nocturia episodes per night.
Patients with overt testosterone deficiency (i.e. levels less than 2.50 ng/mL) were 60% more likely to experience nocturia than those with higher hormone levels.
The researchers also found that "urine production rather than frequency is associated with testosterone deficiency."
The statistical model employed for the study took into consideration age, body mass index, and prostate volume.
Reference- Kim JW, Oh MM, Yoon CY, Bae JH, Kim JJ, Moon DG. Nocturnal polyuria and decreased serum testosterone: Is there an association in men with lower urinary tract symptoms? Int J Urol. 2013 Nov 28. doi: 10.1111/iju.12345.