Low levels of male sex hormones are associated with
increased urine output at night, finds a new study from South Korea. This
association has been found to be independent of both age and prostate volume.
levels of testosterone
male sex hormone, were found to be linked with 93% greater odds for nocturia. Nocturia
condition in which an individual has to wake up at night one or more times for
passing urine. Nocturia has a wide range of causes ranging from increased fluid
intake to malignancies. It becomes more common as people age and occurs in both
men and women.
study included 2180 patients who attended an
outpatient urologic clinic between July 2011 and August 2012 for lower urinary tract symptom
The study found that every 0.142 ng/mL decrease in
testosterone was associated with an increase in the number of nocturia episodes
Patients with overt testosterone deficiency
(i.e. levels less than 2.50 ng/mL) were 60% more likely to experience nocturia
than those with higher hormone levels.
The researchers also found that "urine
production rather than frequency is associated with testosterone deficiency."
The statistical model employed for the study took into
consideration age, body mass index, and prostate volume.
Kim JW, Oh MM, Yoon CY, Bae JH, Kim JJ, Moon DG. Nocturnal
polyuria and decreased serum testosterone: Is there an association in men with
lower urinary tract symptoms? Int J Urol. 2013 Nov 28. doi: 10.1111/iju.12345.