claim that a new nonsurgical treatment called prostate artery embolization
(PAE) may ease the symptoms of benign prostate hyperplasia (BPH), a condition
with an enlarged prostate. BPH
commonly found in men over the age of 50; as the name suggests, it is benign,
i.e. noncancerous. Enlargement of the prostate can cause symptoms that irritate
or obstruct the urinary bladder.
Common Symptoms of BPH Include:
Incomplete emptying of urinary
Increased frequency of urination, esp. during night •
Difficulty in starting the urinary stream •
Decreased force of urination
PAE works by blocking off the arteries that feed the
and making it shrink. PAE was first performed in 2009; it is performed by an interventional
radiologist, rather than a surgeon.
"We have treated more than 100 patients with
[prostate artery embolization] and are encouraged by the excellent reduction in
symptoms and improvement in quality of life for men who have had the procedure,
including some with very large prostates who normally would require open
surgery," Dr. Francisco Carnevale, Associate Professor of Medicine at the University of Sao Paolo.
Researchers claim that 97 percent of the men who
underwent PAE have experienced improvements in symptoms and quality of life.
The study-recorded recurrence of symptoms in 14 percent of patients during a 15
month-long follow up.
"[However], none of our patients have experienced
adverse side effects, and we have followed a number of them for several years
-- longer than other studies," Carnevale said.
The validity of the observation is being widely
debated; the results have been viewed skeptically by the scientific community
since it was a relatively small and short study. Larger trials that compare PAE
with the time-tested treatments available are mandatory before drawing
It is however a promising observation that the
research team has come with.