discovered the effectiveness of Deep Brain Stimulation in curing Alzheimer's,
memory disorders and anorexia.
from the Bonn University of Germany have discovered some amazing effects of
Deep Brain Stimulation in acute depression
. Prof Volker
Arnd Coenen and Prof. Thomas E. Schläpfer published their study in the Journal
have been conducted in the past for assessing the role of Deep Brain
Stimulation on depression. Earlier the area of study focus was nucleus
accumbens but now 'a bundle of nerve fibers running from the limbic system to
the prefrontal cortex was selected - a region known as the medial forebrain bundle'.
The scientists said
that both these regions of the brain are concerned with the feelings of
euphoria and ecstasy.
The experts said that
the therapy is effective when a relatively weak electric current was used.
The scientists from
Bonn University have noticed that six out of seven seriously-depressed test
subjects revealed a marked lowering in depression symptoms such as anxiety,
listlessness, despondence and joylessness within few days of the onset of
treatment. After the treatment, experts monitored the volunteers for 18 months.
In past studies, a
high current was used for the treatment and the results appeared in few weeks
and the treatment was beneficial for only 50 percent of patients. The
scientists at UCLA believed that the success rate of the treatment using
Stimulation of external Trigeminal Nerve on the foreheads of the depressed
volunteers was more effective.
Dr. Rothschild said, "Treatment-resistant
depression is a horrible disease. It can result in death, and people who live
with it often have very difficult lives."
He added, "These impressive
findings in the medial forebrain bundle must now be replicated in a
double-blind fashion, like the study we're doing with Brodmann Area 25 - that's
the way to prove it."
Dr. Rothschild, the
Irving S. and Betty Brudnick Endowed Chair and professor of psychiatry
mentioned, "Every patient knew they were receiving the treatment, which
increases the likelihood of a placebo effect. Studies like these are
important first steps but, until you do the double-blind study in which some
patients have the device turned on, and some do not, and the patients don't
know which group they are in, you can come to inaccurate conclusions."
The scientists concluded that further studies
are needed to ascertain the effectiveness of Deep Brain Stimulation (DBS) in