Benign
prostatic hyperplasia (BPH) is a non-cancerous condition in which the prostate
gland grows too large. BPH and prostatic smooth-muscle contractions are
responsible for lower urinary tract symptoms (LUTS) in men . LUTS include frequent voiding at night
(nocturia), incomplete emptying, hesitancy, weak stream, and frequent and
urgent urination. Finasteride is a drug frequently given to treat prostate
enlargement as it works by reducing the size of the gland.
Dihydrotestosterone
is a hormone that increases the size of the prostate gland. Finasteride belongs
to a class of drugs called 5 alpha reductase inhibitors (5ARI).
Though incompletely
understood, 5ARI reduce the size of prostate partly by blocking the bodys
ability to make dihydrotestosterone.
A recent
study was performed to evaluate the efficacy of finasteride and the results
were published in
The Cochrane Library.
Long-term use of finasteride
improves urinary tract symptoms associated with benign prostatic hyperplasia,
and reduces disease progression. The benefits include reduced risk for
acute urinary retention and the need for surgical intervention.
The
efficacy of finasteride was found to be higher when used in combination with
doxazosin, an alpha blocker. Men with large prostates who use the drugs for at
least 1 year reap more benefits from finasteride compared to those with small
prostates.
Drug-related
adverse effects are uncommon and include slightly increased risk for impotence,
erectile dysfunction, decreased libido, and ejaculation disorder.
The new findings
about finasteride are significant since the worldwide incidence of BPH is on
the rise. Prostate enlargement is common in old age and causes urinary
difficulty. The current evidence is of immense public health importance.
Source-Medindia
I feel good if I can have reasonable and good sexual virility
I take saw palmetto and various other herbal remedies
The wind makes my kidneys or prostate sore
After I swim in the Ocean I urinate very often but pleasing to see the 3/16 " diameter flow of urine
My PSA has come down a bit to 8.1 so I keep away from the biopsy,do you think it's a good idea for failing prostates?
Seamus De Buitleir is animn dom