Preeclampsia is a condition where women develop high
blood pressure and lose protein in the urine during pregnancy after the 20th
week. If the baby is sufficiently
mature, the baby is delivered to prevent complications like bleeding, seizures
and fetal, and sometimes maternal death.
It is a well-known fact that preeclampsia increases
the risk of heart-related deaths in women.
This is especially true in those women who suffer from this condition
before 37 weeks of pregnancy; this is referred to as preterm preeclampsia.
A recent study found a high increase in deaths from
circulatory diseases in women with only one child. Researchers from Norway studied the association between
preeclampsia in the first pregnancy and subsequent mortality from
cardiovascular disease in women with no additional pregnancies.
The study found that:
Women with preterm preeclampsia in the first
pregnancy were at a slightly higher risk for mortality. This higher risk was not noticed in women
with two pregnancies and either preterm or term eclampsia.
women who have had only one child following preterm preeclampsia are at a
ninefold increased risk of mortality due to cardiovascular disease, whereas
women who go on to have a second child have a 2.4-fold high risk
The higher risk of mortality with preterm
preeclampsia was mainly due to an increase in cardiac (heart diseases like
heart attack) and stroke related deaths.
The deaths due to cardiovascular diseases were
also more common in women who had their first child before the age of 30 years.
Women with severe preterm preeclampsia in a single
pregnancy may be unwilling to undergo a second pregnancy due to complications
in the first one, while women with less severe preeclampsia may decide to have
more children. Thus, it is possible
that the severity of preeclampsia is associated with the cardiovascular diseases
rather than the number of children.
Also, the underlying heart disease may deter the woman from having more
The study thus
re-iterates that it is extremely important for women who suffer from preterm
preeclampsia to undergo regular cardiac checkups following delivery to prevent
deaths due to cardiac cause. This is
especially important in those women who have only one child
1. Rolv Skjaerven et al.
Cardiovascular mortality after preeclampsia in one child mothers:
prospective, population based cohort study; BMJ 2012;345:e7677