A 0.5% ivermectin lotion formulation is a safe and effective treatment for head lice, according to a recently published paper in the New England Journal of Medicine. Topical ivermectin was recently approved by the FDA for the treatment of head lice.
Head lice are especially common in children in crowded areas like schools. Local medications like permethrin and pyrethrins are commonly used to treat head lice, though lice are now getting resistant to these treatments. The other options include lindane and malathione, which have questionable safety in children and have an unpleasant odor. Benzyl alcohol and spinosad are other two newer drugs recently approved for the treatment of head lice infestation.
Hair Lice - Beauty Tips
Children who are going to school are facing this problem. A small insect that lives in the hair of children. By applying oil we can overcome from this problem.
Children who are going to school are facing this problem. A small insect that lives in the hair of children. By applying oil we can overcome from this problem.
A recent paper describes the efficacy and safety of 0.5% ivermectin lotion when used in two clinical trials of head-louse infestation carried out in different states of America. All the patients were found to have at least three or more live lice on the scalp or hair before the start of treatment. The patients were given a tube that contained either ivermectin or a vehicle control for the comparison of results. The lotions were to be applied to the hair and scalp for 10 minutes on a single occasion. Adverse effects were assessed by a physician. The efficacy and safety of the drug were evaluated on days 2, 8 and 15 of the study.
The researchers found that out of the 765 individuals who completed the study, topical ivermectin was significantly more effective in treating head lice as compared to the vehicle control; in fact 94.9% patients were louse-free after 1 day of treatment. However, this percentage reduced over the next two assessments (85.2% on day 8 and 73.8% on day 15). This may be due to improper application of the lotion, inadequate exposure of the lotion to louse eggs and re-infestation from other sources.
FDA Approves Sanofi’s Treatment for Head Lice
Pharmaceutical giant Sanofi has revealed that its no-comb treatment for head lice has been approved by the US Food and Drug Administration.
Pharmaceutical giant Sanofi has revealed that its no-comb treatment for head lice has been approved by the US Food and Drug Administration.
Side effects like itching, excoriation of skin and redness were sometimes noted, but these were slightly more common in the group that was administered the vehicle. One patient complained of pain in a limb with the vehicle. Side effects probably attributable to the ivermectin included eye irritation and skin-burning sensation.
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A New Treatment for Head Lice
The FDA has granted its approval to Natroba Topical Suspension 0.9%, a new treatment for controlling head lice.
The FDA has granted its approval to Natroba Topical Suspension 0.9%, a new treatment for controlling head lice.
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Source-Medindia
