- Constipation is one of
the most prevalent conditions encountered in primary care
- Constipation ups kidney disease risk.
- Diagnosis and management of constipation might be helpful for
preventing or treating kidney disease.
The link between constipation
and poor kidney health discovered.
To further explore the
association between constipation and kidney disease, Kovesdy, MD (University of
Tennessee Health Science Center and Memphis VA Medical Center) studied
information on more than 3.5 million US veterans with normal kidney function
who were initially examined in 2004 and 2006 and were followed through 2013.
‘Constipation plays a key role in kidney disease. Treatment by lifestyle modifications and/or use of probiotics could protect patients kidney health.’
- Patients with constipation had a 13% higher likelihood of
developing chronic kidney disease and a 9% higher likelihood of developing
kidney failure compared with patients without
- More severe constipation linked with an
incrementally greater risk for both chronic kidney disease and kidney failure.
"Our findings highlight the
plausible link between the gut and the kidneys and provide additional insights
into the pathogenesis of kidney disease progression," said Dr. Kovesdy. "Our
results suggest the need for careful observation of kidney function trajectory
in patients with constipation, particularly among those with more severe
Constipation - Facts and
Constipation is a condition in which
- fewer than three bowel movements a
- bowel movements with hard, dry stools making them
painful or difficult to pass
is a common condition that can have an impact
on health. For example, constipation is known to boost
heart disease risk, through effects caused by gut bacteria.
It affects 42 million people in
the United States
In the UK,
1 in every 7 adults and up to 1 in every 3 children has constipation at any one
Constipation affects women more
when compared to men, and is common among older adults
and during pregnancy
Study co-authors include Keiichi
Sumida, MD; Miklos Molnar, MD, PhD; Praveen Potukuchi, MS; Fridtjof Thomas,
PhD; Jun Ling Lu, MD; Kunihiro Matsushita, MD, PhD; Kunihiro Yamagata, MD, PhD;
and Kamyar Kalantar-Zadeh, MD, PhD.
Disclosures: Drs. Kovesdy and
Kalantar-Zadeh are employees of the US Department of Veterans Affairs. Opinions
expressed in this paper are those of the authors and do not necessarily
represent the opinion of the Department of Veterans Affairs. The study was
funded by the National Institutes of Health. None of the authors have relevant
conflicts of interest.
Tips to Prevent Constipation
5 Foods that Help Prevent
- Include enough fiber-rich foods
(fruits and vegetables, wholegrain rice and pasta, seeds and oats) in your diet
as it reduces your chances of developing constipation.
plenty of fluids to avoid dehydration
- Never ignore the urge
to have a bowel movement
- Regular exercise helps reduce your
risk of getting constipation
The findings are published in an upcoming issue of the Journal
of the American Society of Nephrology
- Definition and Facts for Constipation -
- Constipation - (http://www.nhs.uk/conditions/Constipation/Pages/Introduction.aspx)
- Constipation - Prevention - (http://www.nhs.uk/Conditions/Constipation/Pages/Prevention.aspx)