Highlights:- Back pain is
commonly treated with Nonsteroidal Anti-inflammatory Drugs (NSAIDs)
- The effectiveness
of NSAIDs in spinal pain has not been established
- The safety of
NSAIDs is also an issue
Nonsteroidal
Anti-inflammatory Drugs (NSAIDs) provide
similar relief of spinal pain as compared to placebo, and at the same time were
associated with side effects, finds a research team from Australia. Their
research was published in the Annals of
the Rheumatic Diseases.
Back pain is a common
ailment for which people consult the doctor. The pain may arise from the bones, joints, ligaments,
tendons, muscles or nerves of the back. Occupations that involve heavy physical
activity with a lot of bending or twisting the back or lifting heavy weights
are common causes of back pain. Conditions like fracture of the vertebrae,
slipping out of intervertebral discs, osteoarthritis and rheumatoid arthritis
are more serious causes of back pain. Conditions like kidney stones and
endometriosis in females that affect abdominal organs can also present with back
pain.
‘Prevention is better than cure, could be the catch phrase in treating back pain.’
While
some of the causes of back pain like slipped disc could require surgical
treatment, most cases of back pain are treated with exercises and painkillers. The
non-steroidal anti-inflammatory drugs (NSAIDs) which include ibuprofen and
diclofenac are often prescribed, while more severe pain may require treatment
with opioids. Opioids have been found to provide only minimal relief as
compared to placebo. Paracetamol is ineffective for spinal pain.
But
are the NSAID painkillers really effective in the treatment of spinal pain? The research
team analyzed 35 well-designed studies to understand the effect of NSAIDS in
spinal pain, as well as their safety when used for this purpose. These studies
included more than 6000 people. They found that:
- NSAIDs did
provide some relief against pain and disability caused by spinal pain, but
the effectiveness was similar to that of a placebo
- Six patients needed to be treated with NSAIDs to bring
about significant pain relief in one patient
- Despite the fact
that the medications were used for a median of only seven days, the risk
of gastrointestinal reactions such as stomach ulcers and bleeding
increased two and a half times
Back pain can be
prevented to a large extent by maintaining a proper posture and avoiding
slouching. Exercises to strengthen the muscles of the back could also reduce
back pain, and thereby medications can be avoided. Additional research is also
necessary to come up with more simple, effective and safe drugs for the
treatment of spinal pain.
Reference:- Machado GC et al. Non-steroidal anti-inflammatory drugs for spinal pain: a systematic review and meta-analysis. Ann Rheum Dis doi:10.1136/annrheumdis-2016-210597
Source-Medindia