disruptor chemicals (EDCs) are found in cosmetics, food packaging and
- Exposure to EDCs
is associated with lower levels of vitamin D.
- Women are found
to have a more pronounced effect than men.
Researchers from The
University of Michigan's Public School of Health have found that Vitamin D
levels are lowered due to exposure to endocrine disrupting chemicals (EDCs)
like Bisphenol A (BPA). This is the first study that was conducted to
understand the impact of endocrine disruptors on the level of vitamin A in the
are chemicals that
affect the endocrine system
of the body, leading to
- Immune effects of
There been more than
1300 studies that have shown that the exposure to endocrine disruptors can lead
to a host of diseases that range from hormone related cancers, obesity,
neurological problems, infertility, obesity and diabetes.
‘Avoid using cosmetics that contain estrogen disruptors to lower risk of vitamin D deficiency.’
Dr. Lauren Johns who is
the first author of the study said "Nearly every person on the planet is
exposed to BPA and another class of endocrine-disrupting chemicals called
phthalates, so the possibility that these chemicals may even slightly reduce vitamin D levels has widespread implications
for public health. Vitamin D plays a broad role in maintaining bone and muscle
health. In addition, low vitamin D levels have been implicated in outcomes of
numerous conditions such as cardiovascular disease, diabetes
EDC Exposure and Vitamin D Levels
The study included 4667
adults who were part of the National Health and Nutrition Examination Survey
(NHANES) which was conducted during the period 2005 and 2010. Blood and urine
samples of the study participants were analyzed, the blood samples were used to
detect the level of vitamin D while the urine samples were used to detect the
concentration of EDC.
The study found that
- Increased in
concentration of phthalates resulted in lower levels of vitamin D
- Women were found
to be more affected by phthalate levels than men
concentration of Bisphenol A in the blood resulted in lower levels of
especially in women
Senior author of the
study, Dr. John D. Meeker said "More research is needed into why an association
exists, but it is possible that EDCs alter the active form of vitamin D in the
body through some of the same mechanisms that they use to impact similar
reproductive and thyroid hormones. Confirmatory studies are needed to show
whether this association exists in other populations."
of Endocrine Disruptors
- Dioxin and dioxin like compounds
- Bisphenol A
Sources of EDCs include
EDCs affect the body by
- Over stimulation
of hormones: EDCs mimic hormones and lead to overstimulation.
- Binding to
receptors: EDCs bind to target receptors and prevent attachment of the
Vitamin D is essential
for proper bone growth and development in the body.
The deficiency of
vitamin D is found to lead to:
- Poor bone development.
- Development of rickets (softening or weakening of bones in
children) or osteomalacia.
- Poor bone density.
- Increased risk for fracture.
- In the NHANES II study, it was found that
the risk of death was lower by 45% when vitamin D levels were above
- Increased risk for cancer.
- Increased risk of infection.
- Increased risk for mental illness.
There are a lot of
complications that are associated with low levels of vitamin D and the presence
of EDCs in commonly used products like cosmetics and children's toys increases
the risk for lowered levels of vitamin D and associated diseases.
- Endocrine Disruptors - (http://www.niehs.nih.gov/health/topics/agents/endocrine/)
- The Estrogenic Endocrine Disrupting Chemical Bisphenol A (BPA) And Obesity - (http://www.ncbi.nlm.nih.gov/pmc/articles/PMC3306519/)
- Vitamin D Insufficiency - (http://www.ncbi.nlm.nih.gov/pmc/articles/PMC3012634/)