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Fat for Healing the Heart

by Himabindu Venkatakrishnan on  July 22, 2014 at 12:25 PM Heart Disease News   - G J E 4
Excess dietary fat is known to cause heart problems, but the right kind of fat helps keep the heart healthy, as revealed in a paper published in The Journal of Experimental Medicine.
 Fat for Healing the Heart
Fat for Healing the Heart
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Unsaturated dietary fatty acids, such as eicosapentaenoic acid (EPA), are known to protect against cardiovascular diseases. However, the mechanism and the specific fat metabolites responsible for this protection were unknown.

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A group of Japanese scientists now show that mice engineered to produce their own EPA are protected against heart disease and have improved cardiac function. One particular EPA metabolite, called 18-hydroxyeicosapentaenoic acid (18-HEPE), was required for this protection. 18-HEPE was produced by immune cells called macrophages, which dampened inflammation and fibrosis in the heart. Treatment with 18-HEPE confirmed its heart-protective effects.

A diet enriched in 18-HEPE might thus help prevent heart failure in patients with cardiovascular diseases.

Source: Eurekalert
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