Relationship between higher-volume treatment
centers and improved overall survival for head and neck cancers has been identified by Yale Cancer Center team researchers.
The findings were presented
September 26 at the American Society for Therapeutic Radiology and
Oncology (ASTRO) meeting in Boston.
‘Patients treated at higher-volume facilities for locally advanced head and neck cancers were more likely to have shorter radiation therapy duration than those at lower volume facilities.’
The research team's findings also
revealed there was a 5.7% decreased hazard of death per additional 20
patients treated per year per facility.
When annual facility case volume
was defined based on a threshold of 95 cases/year (90th percentile),
there was a 17.5% decreased hazard of death for higher-volume versus
"Our findings suggest a strong
relationship between higher-volume radiation therapy facilities and
improved overall survival for patients treated with IMRT for locally
advanced head and neck cancers," said Henry S. Park, MD, MPH, first
author on the study and a chief resident in the Department of
Therapeutic Radiology at Yale School of Medicine.
should focus on the role of other factors potentially underlying this
association, including radiation contouring, education,
multidisciplinary communication, and toxicity management."