Precocious Puberty - Causes - Symptoms - Diagnosis - Treatment - FAQs
The period of maturation of sexual and physical characteristics is known as puberty and when these bodily changes happen before time it is known as ‘precocious puberty’.
The period of maturation of sexual and physical characteristics is known as puberty and when these bodily changes happen before time it is known as ‘precocious puberty’.
‘Chemical modifications of the human genome (epigenetic modification) occur when girls and boys enter puberty. The identified epigenetic changes during puberty are therefore the best lead towards understanding how environmental factors can affect pubertal onset’
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Further, highly specific changes in a child's DNA methylation -- a process by which methyl groups are added to DNA-- could differentiate children according to whether they had entered puberty or not and thus may be used to predict a child's pubertal stage. "Changes in the DNA methylation patterns can be caused by many different factors. However, we could see very specific changes when children went through puberty, and have subsequently shown that this also leads to changes in the expression of the methylated genes," said lead researcher Kristian Almstrup from Rigshospitalet in Copenhagen.
Due to the changes in the epigenetic control of the gene, the "puberty genes" TRIP6 -- Thyroid Hormone Receptor Interactor 6, has been found to increasingly express through puberty.
Obesity, Gestational Diabetes in Mother Increases Risk of Early Puberty in Child
Daughters born to overweight mothers with gestational diabetes are more likely to experience an earlier onset of one sign of puberty.
Daughters born to overweight mothers with gestational diabetes are more likely to experience an earlier onset of one sign of puberty.
"The study demonstrates how the environment can affect the pubertal onset in humans. It gives us a significant insight in to the crucial role of epigenetic factors on our reproductive development," added Anders Juul, Professor at Rigshospitalet in Copenhagen.
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Baby Boy Attends Puberty at the Age of 1 in Delhi
Akash, a one-year-old baby boy in Delhi, has developed fully grown sex organs and experienced sexual desires similar to a 25-year-old man.
Akash, a one-year-old baby boy in Delhi, has developed fully grown sex organs and experienced sexual desires similar to a 25-year-old man.
They found a number of areas in the human genome, which is controlled epigenetically during puberty.
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Female Pelvis Widens After Puberty and Narrows With Menopause
With the onset of puberty, the male pelvis remains the same. But the female pelvis becomes wider and reaches its full width around the age of 25-30 years.
With the onset of puberty, the male pelvis remains the same. But the female pelvis becomes wider and reaches its full width around the age of 25-30 years.
Source-IANS
