Drugs To Treat Gout May Prevent Alcohol-Induced Liver Disease, Inflammation

by Shirley Johanna on  August 1, 2015 at 12:39 PM Drug News
RSS Email Print This Page Comment bookmark
Font : A-A+

Two drugs that are commonly used to treat gout may protect from alcohol-induced liver disease and inflammation, says a new study.

The findings suggest that clinical trials in humans with alcoholic liver disease should be considered.
Drugs To Treat Gout May Prevent Alcohol-Induced Liver Disease, Inflammation
Drugs To Treat Gout May Prevent Alcohol-Induced Liver Disease, Inflammation

"This study should ultimately help patients with alcoholic liver disease to prevent or treat acute episodes of alcoholic hepatitis, a potentially lethal condition," said Gyongyi Szabo, researcher at University of Massachusetts.

To make this discovery, Szabo and colleagues used immune cells from human volunteers as well as four groups of mice.

In the human cell experiments, immune cells were isolated and exposed to alcohol-treated human hepatocytes in a test tube.

Results indicated that uric acid and ATP - components released from alcohol-damaged hepatocytes - activated the inflammasome, a component of the innate immune system.

"The link between alcohol induced tissue damage and sensing by the immune system through the inflammasome opens the door for new therapeutics targeting this type of inflammation in liver diseases," explained John Wherry, deputy editor of the Journal of Leukocyte Biology that published the paper.

Source: IANS

Post a Comment

Comments should be on the topic and should not be abusive. The editorial team reserves the right to review and moderate the comments posted on the site.
Notify me when reply is posted
I agree to the terms and conditions

Related Links

More News on:

Drug Toxicity Gout Hepatitis A Liver Wilson's Disease Drugs Banned in India Anti-Inflammatory Diet Milk Thistle Current Treatments for Liver Cancer Fatty Liver Disease: A Growing Health Problem in India 

News A - Z

A B C D E F G H I J K L M N O P Q R S T U V W X Y Z

News Search

Medindia Newsletters

Subscribe to our Free Newsletters!

Terms & Conditions and Privacy Policy.

Find a Doctor
Advertisement

Stay Connected

  • Available on the Android Market
  • Available on the App Store

Facebook

News Category

News Archive