Drug Given 24-Hours After Nuclear Radiation Exposure Increases Survival Rates

by Lakshmi Darshini on  August 24, 2015 at 12:32 PM Drug News
RSS Email Print This Page Comment bookmark
Font : A-A+

People exposed to nuclear radiation may have higher chances of survival when they are given an injection, a day after the exposure, says a study.
Drug Given 24-Hours After Nuclear Radiation Exposure Increases Survival Rates
Drug Given 24-Hours After Nuclear Radiation Exposure Increases Survival Rates

In the experiment, a single injection of the investigative peptide drug TP508 given 24 hours after a potentially-lethal exposure to radiation significantly increased survival and delayed mortality in mice by counteracting damage to the gastrointestinal system.

"The peptide may be an effective emergency nuclear countermeasure after exposure to increase survival," said lead author Carla Kantara from The University of Texas Medical Branch (UTMB) in the US.

The drug was originally developed for use in stimulating repair of skin, bone and muscle tissues. In clinical trials, the drug has been reported to increase healing of diabetic foot ulcers and wrist fractures with no drug-related adverse events.

The threat of a nuclear incident has raised global awareness about the need for medical countermeasures that can prevent radiation-induced damage, even if given a day or more after contact with nuclear radiation.

"Because radiation-induced damage to the intestines plays a key role in how well a person recovers from radiation exposure, it is crucial to develop novel medications capable of preventing GI damage," said Darrell Carney, adjunct professor in biochemistry and molecular biology at UTMB.

The study appeared in the journal Laboratory Investigation.

Source: IANS

Post a Comment

Comments should be on the topic and should not be abusive. The editorial team reserves the right to review and moderate the comments posted on the site.
Notify me when reply is posted
I agree to the terms and conditions

Related Links

More News on:

Drug Toxicity Radioisotope Scan Radiotherapy X-Ray Signature Drug Toxicity Radiation Hazards Acute Radiation Syndrome 

News A - Z

A B C D E F G H I J K L M N O P Q R S T U V W X Y Z

News Search

Medindia Newsletters

Subscribe to our Free Newsletters!

Terms & Conditions and Privacy Policy.

Find a Doctor

Stay Connected

  • Available on the Android Market
  • Available on the App Store

News Category

News Archive

Loading...