Advertisement

Diluted Surfactants Show Better Drug Absorption in Respiratory Distress Syndrome

by Julia Samuel on  July 16, 2015 at 3:49 PM Medical Gadgets
RSS Email Print This Page Comment
Font : A-A+

The ability of a lung to accept medication can make the difference between life and death as every lung is unique.
Diluted Surfactants Show Better Drug Absorption in Respiratory Distress Syndrome
Diluted Surfactants Show Better Drug Absorption in Respiratory Distress Syndrome

Researchers at University of Michigan discovered a 3D lung simulation and tested three controversial studies that used surfactant replacement therapy to treat acute respiratory distress syndrome (ARDS) in adults.

Surfactant replacement is successfully used in neonates lacking in natural surfactant, but adults with ARDS who seemingly should benefit from the therapy have shown mixed and limited results.

Surfactant replacement therapy, delivers a liquid medication into the lungs that makes it easier for them to inflate. It's widely used to treat a similar condition in premature babies, who sometimes lack the surfactant necessary to expand their lungs.

Researchers simulated the methods used in the different studies and ran them on virtual models of patient lungs to figure out which factors may be creating this disconnect. Diluted preparation of the surfactant allowed the medication to penetrate considerably deeper into the lungs reducing mortality by about half.

The same technology may be used to model patient lungs in clinical settings, extrapolating the optimal drug formulation and administration that will best fit each unique case.



Source: Medindia

Post a Comment

Comments should be on the topic and should not be abusive. The editorial team reserves the right to review and moderate the comments posted on the site.
Notify me when reply is posted
I agree to the terms and conditions

Related Links

More News on:

Small Intestine Biopsy Drug Toxicity Patent Ductus Arteriosus Signature Drug Toxicity Asbestosis Respiratory Distress Syndrome Meconium Aspiration Syndrome Psychological Defence Mechanisms 

News A - Z

A B C D E F G H I J K L M N O P Q R S T U V W X Y Z

News Search

Advertisement

Medindia Newsletters

Subscribe to our Free Newsletters!

Terms & Conditions and Privacy Policy.

Advertisement
Advertisement

Stay Connected

  • Available on the Android Market
  • Available on the App Store

Facebook

News Category

News Archive