Metal-Organic Frameworks (MOFs) : New Way to Deliver Painkillers For Longer-lasting Pain Relief
Painkillers like ibuprofen are packed inside metal-organic frameworks (MOFs) to provide longer-lasting pain relief, reveals study.
Painkillers like ibuprofen are packed inside metal-organic frameworks (MOFs) to provide longer-lasting pain relief, reveals study.
‘Taking any dose of NSAIDs -- such as ibuprofen, diclofenac, celecoxib and naproxen-- for one week, one month or more than a month was associated with an increased risk of heart attack.’
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The study, published in the journal The BMJ, found that taking any dose of NSAIDs -- such as ibuprofen, diclofenac, celecoxib and naproxen-- for one week, one month or more than a month was associated with an increased risk of heart attack. "Given that the onset of risk of acute myocardial infarction occurred in the first week and appeared greatest in the first month of treatment with higher doses, prescribers should consider weighing the risks and benefits of NSAIDs before instituting treatment, particularly for higher doses," said Michele Bally from the University of Montreal.
For their study, the researchers carried out a systematic review and a meta-analysis and analysed results on 446,763 people of whom 61,460 had a heart attack.
Painkiller Abuse in Animals Can be Avoided by Targeting Opioid Receptors Outside the Brain
Painkiller drug abuse in rats can be avoided by targeting delta receptors in the peripheral tissues instead of mu receptors in the brain.
Painkiller drug abuse in rats can be avoided by targeting delta receptors in the peripheral tissues instead of mu receptors in the brain.
Painkiller Misuse Shows Strong Link To Starting Heroin Use Among Veterans
Veterans who began misusing opioid painkillers were more likely to start using heroin compared to non-users.
Veterans who began misusing opioid painkillers were more likely to start using heroin compared to non-users.
Newly Identified Synthetic Painkiller Could Help Replace Morphine
A newly identified synthetic drug appears to neutralize pain as effectively as morphine but without the side-effects that make opioids so dangerous and addictive.
A newly identified synthetic drug appears to neutralize pain as effectively as morphine but without the side-effects that make opioids so dangerous and addictive.
