Compounds in Monster Radish Can Help Prevent Heart Disease

Compounds found in "monster" radish or Sakurajima Daikon can help protect coronary blood vessels and is likely to prevent heart disease and stroke, reports a new study. The findings of the study are published in the Journal of Agricultural and Food Chemistry.

Step aside carrots, onions, and broccoli. The newest heart-healthy vegetable could be a gigantic, record-setting radish.

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‘Radish can lower high blood pressure and the threat of clots (a pair of risk factors for heart attack and stroke) as it is an excellent source of antioxidants.’

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In the study, scientists state that compounds found in the Sakurajima Daikon, or "monster," radish could help protect coronary blood vessels and potentially prevent heart disease and stroke.

The finding could lead to the discovery of related substances in other vegetables and perhaps lead to new drug treatments.

Grown for centuries in Japan, the Sakurajima Daikon is one of the Earth's most massive vegetables. In 2003, the Guinness Book of World Records certified a Sakurajima weighing nearly 69 pounds as the world's heaviest radish.

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Radishes are good sources of antioxidants and reportedly can reduce high blood pressure and the threat of clots, a pair of risk factors for heart attack and stroke. But to date, no studies have directly compared the heart-health benefits of the Sakurajima Daikon to other radishes.

To address this knowledge gap, Katsuko Kajiya and colleagues sought to find out what effects this radish would have on nitric oxide production, a key regulator of coronary blood vessel function, and to determine its underlying mechanisms.

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The researchers exposed human and pig vascular endothelial cells to extracts from Sakurajima Daikon and smaller radishes. Using fluorescence microscopy and other analytical techniques, the research team found the Sakurajima Daikon radish induced more nitric oxide production in these vascular cells than a smaller Japanese radish.

They also identified trigonelline, a plant hormone, as the active component in Sakurajima Daikon that appears to promote a cascade of changes in coronary blood vessels resulting in improved nitric oxide production.

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Source-Eurekalert