Compound Formula Rehmannia Alleviates Levodopa-Induced Dyskinesia in Parkinson's Disease

by Bidita Debnath on  August 8, 2014 at 10:01 PM Research News
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For Parkinson's disease, Levodopa is the preferred treatment in the clinic.
 Compound Formula Rehmannia Alleviates Levodopa-Induced Dyskinesia in Parkinson's Disease
Compound Formula Rehmannia Alleviates Levodopa-Induced Dyskinesia in Parkinson's Disease

However, long-term use of levodopa may lead to various motor complications, among which levodopa-induced dyskinesia is the most common, severely affecting patients' quality of life. Dr. Jiancheng He and co-workers from Shanghai University of Traditional Chinese Medicine in China established a model of Parkinson's disease dyskinesia in rats, and treated these animals with Compound Formula Rehmannia.

They found that Compound Formula Rehmannia alleviates levodopa-induced dyskinesia in Parkinson's disease by modulating neurotransmitter signaling in the corpus striatum. The relevant article has been published in the Neural Regeneration Research (Vol. 9, No. 4, 2014).

Source: Eurekalert

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