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Combination Drug to Set Off Self-destruct Process in Lung Cancer Cells Discovered

by Sushma Rao on  November 1, 2014 at 10:56 PM Cancer News   - G J E 4
A combination drug that can set off the self-destruct process in lung cancer cells has been discovered.
Combination Drug to Set Off Self-destruct Process in Lung Cancer Cells Discovered
Combination Drug to Set Off Self-destruct Process in Lung Cancer Cells Discovered
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Using lung cancer cells and mice the Cancer Research UK team, based at the UCL Cancer Institute scientists, showed that the combination of two drugs, called TRAIL and a CDK9 inhibitor, altered the molecular switches in the cell suicide process, hence forcing the cancer cells to self-destruct.

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Lead researcher, Cancer Research UK scientist Professor Henning Walczak from the UCL Cancer Institute, said that igniting the fuse that caused lung cancer cells to self-destruct could pave the way to a completely new treatment approach.

Nell Barrie, senior science information manager at Cancer Research UK, added that understanding and targeting these processes would help move closer to the goal of 3 out of 4 people beating cancer within the next 20 years.

The research is due to be presented at the National Cancer Research Institute (NCRI) Cancer Conference in Liverpool.
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