Scientists have now found the reason behind the onset of chronic diseases.
The discovery marks a significant step towards understanding the complex processes involved in the hypoxic response which, when it malfunctions, can cause and affect the progress of many types of serious disease, including cancer.
Scientists at Barts Cancer Institute at Queen Mary, University of London and The University of Nottingham have uncovered a previously unknown level of hypoxic regulation at a molecular level in human cells, which could provide a novel pathway for the development of new drug therapeutics to fight disease.
The cutting-edge work was funded by the Biotechnology and Biological Sciences Research Council (BBSRC).
The finding has been published in the international journal Nature Cell Biology.