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Cancer Progression Promoted by Junk DNA

by Kathy Jones on  June 4, 2013 at 7:12 PM Genetics & Stem Cells News   - G J E 4
Scientists at The University of Nottingham have found that at least one genetic malfunction in a sequence considered junk DNA promotes cancer growth.
 Cancer Progression Promoted by Junk DNA
Cancer Progression Promoted by Junk DNA
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The researchers, led by Dr Cristina Tufarelli, in the School of Graduate Entry Medicine and Health Sciences, discovered that the presence of this faulty genetic element - known as chimeric transcript LCT13 - is associated with the switching off of a known tumour suppressor gene (known as TFPI-2) whose expression is required to prevent cancer invasion and metastasis.

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Their findings suggest that LCT13 may be involved in switching off TFPI-2.

The study has been published in the journal Nucleic Acid Research.

Source: ANI
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